Yes, X-Chromosome defects can impair vision in boys. A genetic disorder of the X-Chromosome can lead to juvenile retinoschisis. Juvenile Retinoschisis is caused due to a defective gene(RS1). This gene produces an amino acid that can affect the photoreceptors(light sensitive pigments) in the eye.
Juvenile Retinoschisis can bring physical changes in the retina(sometimes, the retina may be split into two) which can impair vision permanently.
X-Chromosome Defects Can Impair Vision in Boys: Like, already mentioned,X-Chromosome defects lead to the development of juvenile retinoschisis.
This means that this disorder can be particular primarily among boys(since boys have only X-Chromosome). Sometimes, there is a possibility of this disorder even among girls.(due to the presence of two defective genes).
Symptoms of Juvenile Retinoschisis: Juvenile retinoschisis causes gradual loss of vision in children. Due to the physical changes occurring in the retina, the following symptoms can be observed:
- Retinal detachment due to the formation of holes in the eye.
- Cyst development and blood vessel disruption in the retinal between layers.
- Vitreous haemorrhage(leakage of blood into the eye).
- Maculation’s function can change, leading to loss of clear vision.
- Rapid and involuntary eye movements are also observed in individuals suffering from juvenile retinoschisis.
Diagnosing Juvenile Retinoschisis: This disease can be detected during infancy. But, sometimes it may not be observed and can be diagnosed until the child grows a little older.
- A child suffering from this disease may not be aware of it’s presence and would suffer from gradual loss in vision.
- Different imaging techniques like optical coherence tomography (OCT) are now available to clearly detect and differentiate juvenile retinoschisis from other eye diseases.
- Also, an electroretinogram can be used to find out the the retinal problems.
- Various gene tests are also available for finding out the presence of defective RS1 genes.
Treating Juvenile Retinoschisis: Unfortunately, there is no treatment for this disorder and it’s progress can’t be halted.
- Performing a surgery may be necessary in case there is a retinal detachment or to deal with vitreous haemorrhage.
- Low vision aids and adaptive skills training can be useful in dealing with vision loss.
- Identifying family members with defective RS1 genes can prove to be helpful.
X-Chromosome defects can impair vision in boys due to the development of juvenile retinoschisis which is in-fact a genetic defect of the X-Chromosome.
